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Minimal impact on cortisol or prolactin levels

Accumulation of caveolin in the endoplasmic reticulum redirects the protein to lipid storage droplets

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[PMC free article: PMC11168245] [PubMed: 38547961] 406

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It is also important to note that these medications were well tolerated by these groups of patients without major adverse effects described in the evaluated trials. Specifically, GLP-1 RAs produced a mean weight loss of 5.03 kg (corresponding to 4.15% body weight reduction) compared to controls, along with significant improvements in BMI (1.59 kg/m), waist circumference (3.40 cm), and fasting glucose (0.29 mmol/L)